Osmosis StemFactor Growth Factor Serum

I’ve been working my way through a few Osmosis items and next up is the StemFactor Growth Factor Serum. Details per Osmosis:

Reverse aging by stimulating new cells and rebuilding collagen and elastin with this revolutionary serum. StemFactor features advanced exosome technology to maximize the delivery of over 600 growth factors and skin proteins derived from adult stem cells that are easily recognized by the skin to improve all aspects of skin damage and aging. This unique lightweight serum inspires the skin for a radiant, youthful complexion.

Directions Apply 1-2 pumps morning and evening.

This serum has an almost clear color, it’s texture is a lightly hydrating liquid gel. This absorbs very quickly and is never sticky. It’s such an easy serum to use & I love the airless pump. Osmosis is a medical grade skincare brand based out of Evergreen, CO. They believe in a holistic approach to beauty-Our unique philosophy is based on analyzing the skin and body as a whole to treat skin conditions at their source, restoring beauty and wellness. Our wellness system is a program designed to optimize the skin and body’s rejuvenation process. We holistically take aim at the origin of imbalances to impart real change. Using a multi-tiered approach we partner with the skin to remodel and heal without causing inflammation.

StemFactor is a serum for all skin types designed to promote new cell growth and enhance immune function. This serum is basically growth factors from human stem cells. Stem cells are those beginning cells that haven’t specialized yet meaning they can become any type of cell. There’s quite a bit of research in healthcare about stem cells and it was only natural that one day they be geared towards skincare too. Growth factors are produced by the body to regulate the division and production of cells. Growth factors protect the skin and help stimulate the growth of new cells. You’re trying to encourage multiple types of cells to grow to repair and replace damaged cells. Sounds great for anti-aging right? It is. I find these types of serums give me that healthy glow, almost like a pregnancy glow. It’s a healthy radiant complexion look. It’s not going to take all your wrinkles away or magically erase every issue you have, nothing is that powerful in a bottle. Think of growth factor serums as the healthy complexion giver.

Now there are multiple medical grade skincare lines putting out growth factor serums. This is what Osmosis says is different about their Growth Factors: Beyond having higher numbers and a more complete collection of growth factors that result from combining fibroblasts and stem cells, we have evolved our growth factors. This means we have perfected a way to complete the growth factor manufacturing process by creating exosomes. Exosomes are protective envelopes that surround each growth factor allowing it to have a longer life, better penetration, and more activation at the receptor site.


These are the growth factors in their product:

HGF (Hepatocyte Growth Factor): Enhances wound repair and increases the number of macrophages for scar tissue removal.

TGF-B (Transforming Growth Factor Beta): Increases new blood vessel formation and collagen production.

FGF (Fibroblast Growth Factor): Elevates the number of collagen manufacturing cells along with increasing their production levels.

IFNg (Interferon Gamma): Fights viral and bacterial infections and increases ‘Natural Killer’ cell activity.

PDGF-AA (Platelet Derived Growth Factor): Creates new fibroblasts, increases the number of macrophages, increases angiogenesis, and new cell development.

GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor): Stimulates immune cell production.

GF1 (Insulin-like Growth Factor): Promotes cell growth and proliferation.

VEGF (Vascular Endothelial Growth Factor): Increases new blood vessel formation.

KGF (Keratinocyte Growth Factor): Increases production of epithelial cells.


Growth factors in this case are from human fat stem cells that are transferred into a culture growth media. They grow them in a lab essentially. The stem cells divide and secrete growth factors and cytokines. They collect the growth factors and leave behind the stem cells to keep diving and producing more. There are three articles on the Osmosis site that explain the whole stem cells/growth factors in much more depth: HERE, HERE & HERE. Now these serums aren’t for everyone. Just as snail mucin isn’t either. Either you want to try it or not. I personally love growth factor serums for their ability to give that healthy glow. Most growth factor serums are pricey because of the costly growth and extraction process.

I find some growth factor serums are better than others. The more growth factors present in the serum the better it’s going to be. Osmosis StemFactor usually gets a 5 star rating online, it seems to be very popular. It was easy to use, sinks right in and layers easily. That being said,  I didn’t really notice that much from using it sadly. It just didn’t seem to work for me as well as I had hoped. I feel like the lemon since it seems to be popular for most. So just because it didn’t work for me doesn’t mean it won’t for you. My skin felt healthier to some degree it just wasn’t as radiant as when I used another brand of stem cell serum.


Water (Aqua), Human Stem Cell Conditioned Media, Human Fibroblast Conditioned Media, Hamamelis Virginiana (Witch Hazel) Bark/Leaf/Twig Extract, Hydroxyethylcellulose, Phosphatidylcholine, Citrus Medica Limonum (Lemon) Oil, Dehydroacetic Acid, Benzyl Alcohol.

*I received this product free to test

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